Structure of the copper sites in membrane-bound cytochrome c oxidase.
01 January 1986
The structures of membrane proteins are difficult to obtain by crystallography, and may be altered by the detergents used in their extraction. X-ray absorption spectroscopy has been used to identify the structures of the copper atoms of the membrane- bound enzyme in mitochondria and in submitochondrial particles (SMP) at respective concentrations of 100 and 200 mu molar copper.